Kir3.4 (KCNJ5) Antibodies

Antibodies that detect Kir3.4 (KCNJ5) can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Kir3.4 (KCNJ5) in Human, Mouse and Rat samples. Our Kir3.4 (KCNJ5) polyclonal and... Antibodies that detect Kir3.4 (KCNJ5) can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Kir3.4 (KCNJ5) in Human, Mouse and Rat samples. Our Kir3.4 (KCNJ5) polyclonal and monoclonal antibodies are developed in Rabbit... Antibodies that detect Kir3.4 (KCNJ5) can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Kir3.4 (KCNJ5) in Human, Mouse and Rat samples. Our Kir3.4 (KCNJ5) polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative expression to confirm specificity to Kir3.4 (KCNJ5). Find the Kir3.4 (KCNJ5) antibody that fits your needs. Choose from 1 of 13 Kir3.4 (KCNJ5) antibodies, which have been validated in experiments with 2 publications and 22 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced... Antibodies that detect Kir3.4 (KCNJ5) can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Kir3.4 (KCNJ5) in Human, Mouse and Rat samples. Our Kir3.4 (KCNJ5) polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative expression to confirm specificity to Kir3.4 (KCNJ5). Find the Kir3.4 (KCNJ5) antibody that fits your needs. Choose from 1 of 13 Kir3.4 (KCNJ5) antibodies, which have been validated in experiments with 2 publications and 22 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

G protein-coupled inwardly rectifying potassium channels (Kir3.1 through Kir3.4) are coupled to numerous neurotransmitter receptors in the brain and are abundantly expressed in the olfactory bulb, hippocampus, neocortex, dentate gyrus, cerebellar cortex and thalamus regions of the brain. Also known as GIRK, Kir3 potassium channels localize to the soma and dendrites as well as axons of neurons. Liberated Gbg subunits from G protein heterotrimers bind to and regulate Kir3 channel activity. Gb3- and Gb4-containing Gbg dimers bind directly to cytoplasmic domains of Kir3 proteins and increase the K+ current while Gb5-containing Gbg dimers inhibit Kir3 K+ current. Kir3 activity is also inhibited by tyrosine phosphorylation. Brain-derived neurotrophic factor activates receptor tyrosine kinase B, which then phosphorylates Kir3 tyrosine residues, effectively inactivating the Kir3 channels.

Synonyms

cardiac ATP-sensitive potassium channel; cardiac inward rectifier; CIR; G protein-activated inward rectifier potassium channel 4; GIRK4; GIRK-4; Heart KATP channel; inward rectifier K(+) channel Kir3.4; inward rectifier K+ channel KIR3.4; IRK4; IRK-4; KATP1; KATP-1; KCNJ5; Kir3.4; LQT13; Potassium channel, inwardly rectifying subfamily J member 5; potassium channel, inwardly rectifying subfamily J, member 5; potassium inwardly-rectifying channel, subfamily J, member 5; potassium voltage-gated channel subfamily J member 5

Kir3.4 (KCNJ5) Antibodies

Target Information

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